General Structure Information
| PDB ID | 1h7u |
| HGNC Gene Label(s) | PMS2 |
| Structure Name | hpms2-atpgs |
| Resolution | 2.7Å |
| Reference | AUTH A.GUARNE,M.S.JUNOP,W.YANGTITL STRUCTURE AND FUNCTION OF THE N-TERMINAL 40 KDA FRAGMENT OFTITL 2 HUMAN PMS2: A MONOMERIC GHL ATPASEREF EMBO J. V. 20 5521 2001REFN ISSN 0261-4189PMID 11574484DOI 10.1093/EMBOJ/20.19.5521 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 302 |
| Number Of SNVs | 102 |
| Number Of Permutations | 17905 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.016 |
| p-value | 0.802 |
ClinVar
| Number Of Residues | 302 |
| Number Of SNVs | 3 |
| Number Of Permutations | 221 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.0 |
| p-value | 0.511 |
COSMIC
| Number Of Residues | 302 |
| Number Of SNVs | 3 |
| Number Of Permutations | 109 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.494 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 102 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.299 |
| p-value | 0.53 |
Cosmic vs. ExAC
