General Structure Information
| PDB ID | 2xbb |
| HGNC Gene Label(s) | NEDD4 |
| Structure Name | nedd4 hect:ub complex |
| Resolution | 2.68Å |
| Reference | AUTH E.MASPERO,S.MARI,E.VALENTINI,A.MUSACCHIO,A.FISH,AUTH 2 S.PASQUALATO,S.POLOTITL STRUCTURE OF THE HECT:UBIQUITIN COMPLEX AND ITS ROLE INTITL 2 UBIQUITIN CHAIN ELONGATIONREF EMBO REP. V. 12 342 2011REFN ISSN 1469-221XPMID 21399620DOI 10.1038/EMBOR.2011.21 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 376 |
| Number Of SNVs | 101 |
| Number Of Permutations | 27692 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.014 |
| p-value | 0.148 |
COSMIC
| Number Of Residues | 376 |
| Number Of SNVs | 5 |
| Number Of Permutations | 540 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.2 |
| p-value | 0.949 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 101 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.26 |
| p-value | 0.521 |