General Structure Information
| PDB ID | 3f81 |
| HGNC Gene Label(s) | DUSP3 |
| Structure Name | interaction of vhr with sa3 |
| Resolution | 1.9Å |
| Reference | AUTH S.WU,S.VOSSIUS,S.RAHMOUNI,A.V.MILETIC,T.VANG,AUTH 2 J.VAZQUEZ-RODRIGUEZ,F.CERIGNOLI,Y.ARIMURA,AUTH 3 S.WILLIAMS,T.HAYES,M.MOUTSCHEN,S.VASILE,AUTH 4 M.PELLECCHIA,T.MUSTELIN,L.TAUTZTITL MULTIDENTATE SMALL-MOLECULE INHIBITORS OF VACCINIATITL 2 H1-RELATED (VHR) PHOSPHATASE DECREASE PROLIFERATIONTITL 3 OF CERVIX CANCER CELLS.REF J.MED.CHEM. V. 52 6716 2009REFN ISSN 0022-2623PMID 19888758DOI 10.1021/JM901016K |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 179 |
| Number Of SNVs | 42 |
| Number Of Permutations | 14288 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.02 |
| p-value | 0.762 |
COSMIC
| Number Of Residues | 179 |
| Number Of SNVs | 4 |
| Number Of Permutations | 110 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.181 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.228 |
| p-value | 0.595 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
