General Structure Information
| PDB ID | 3vbb |
| HGNC Gene Label(s) | SARS |
| Structure Name | crystal structure of seryl-trna synthetase from human at 2.9 angstroms |
| Resolution | 2.89Å |
| Reference | AUTH X.XU,Y.SHI,H.M.ZHANG,E.C.SWINDELL,A.G.MARSHALL,M.GUO,AUTH 2 S.KISHI,X.L.YANGTITL UNIQUE DOMAIN APPENDED TO VERTEBRATE TRNA SYNTHETASE ISTITL 2 ESSENTIAL FOR VASCULAR DEVELOPMENT.REF NAT COMMUN V. 3 681 2012REFN ESSN 2041-1723PMID 22353712DOI 10.1038/NCOMMS1686 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 440 |
| Number Of SNVs | 68 |
| Number Of Permutations | 69354 |
| Optimal Distance Threshold | 34.0 |
| K Statistic | 0.425 |
| p-value | 0.003 |
COSMIC
| Number Of Residues | 440 |
| Number Of SNVs | 4 |
| Number Of Permutations | 672 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.062 |
| p-value | 0.353 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
