General Structure Information
| PDB ID | 3hy4 |
| HGNC Gene Label(s) | MTHFS |
| Structure Name | structure of human mthfs with n5-iminium phosphate |
| Resolution | 2.79Å |
| Reference | AUTH D.WU,Y.LI,G.SONG,C.CHENG,R.ZHANG,A.JOACHIMIAK,AUTH 2 N.SHAW,Z.-J.LIUTITL STRUCTURAL BASIS FOR THE INHIBITION OF HUMANTITL 2 5,10-METHENYLTETRAHYDROFOLATE SYNTHETASE BYTITL 3 N10-SUBSTITUTED FOLATE ANALOGUESREF CANCER RES. V. 69 7294 2009REFN ISSN 0008-5472PMID 19738041DOI 10.1158/0008-5472.CAN-09-1927 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 195 |
| Number Of SNVs | 40 |
| Number Of Permutations | 4085 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.903 |