General Structure Information
| PDB ID | 2lnx |
| HGNC Gene Label(s) | VAV2 |
| Structure Name | solution structure of vav2 sh2 domain |
| Resolution | -1.0Å |
| Reference | AUTH B.WU,F.WANG,J.ZHANG,Z.ZHANG,L.QIN,J.PENG,F.LI,J.LIU,G.LU,AUTH 2 Q.GONG,X.YAO,J.WU,Y.SHITITL IDENTIFICATION AND STRUCTURAL BASIS FOR A NOVEL INTERACTIONTITL 2 BETWEEN VAV2 AND ARAP3.REF J.STRUCT.BIOL. V. 180 84 2012REFN ISSN 1047-8477PMID 22750419DOI 10.1016/J.JSB.2012.06.011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 113 |
| Number Of SNVs | 30 |
| Number Of Permutations | 3450 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.106 |
| p-value | 0.023 |
COSMIC
| Number Of Residues | 113 |
| Number Of SNVs | 3 |
| Number Of Permutations | 168 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.333 |
| p-value | 0.846 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 30 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.168 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
