General Structure Information
| PDB ID | 1ihi |
| HGNC Gene Label(s) | AKR1C2 |
| Structure Name | crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with nadp+ and ursodeoxycholate |
| Resolution | 3.0Å |
| Reference | AUTH Y.JIN,S.E.STAYROOK,R.H.ALBERT,N.T.PALACKAL,AUTH 2 T.M.PENNING,M.LEWISTITL CRYSTAL STRUCTURE OF HUMAN TYPE IIITITL 2 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/BILE ACIDTITL 3 BINDING PROTEIN COMPLEXED WITH NADP(+) ANDTITL 4 URSODEOXYCHOLATE.REF BIOCHEMISTRY V. 40 10161 2001REFN ISSN 0006-2960PMID 11513593DOI 10.1021/BI010919A |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 320 |
| Number Of SNVs | 46 |
| Number Of Permutations | 5778 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.084 |
| p-value | 0.0 |
ClinVar
| Number Of Residues | 320 |
| Number Of SNVs | 3 |
| Number Of Permutations | 159 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.0 |
| p-value | 0.801 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 46 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.226 |
| p-value | 0.482 |