General Structure Information
| PDB ID | 1mzd |
| HGNC Gene Label(s) | GZMK |
| Structure Name | crystal structure of human pro-granzyme k |
| Resolution | 2.9Å |
| Reference | AUTH C.HINK-SCHAUER,E.ESTEBANEZ-PERPINA,E.WILHARM,AUTH 2 P.FUENTES-PRIOR,W.KLINKERT,W.BODE,D.E.JENNETITL THE 2.2-A CRYSTAL STRUCTURE OF HUMAN PRO-GRANZYMETITL 2 K REVEALS A RIGID ZYMOGEN WITH UNUSUAL FEATURESREF J.BIOL.CHEM. V. 277 50923 2002REFN ISSN 0021-9258PMID 12384499DOI 10.1074/JBC.M207962200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 227 |
| Number Of SNVs | 68 |
| Number Of Permutations | 12484 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.217 |
| p-value | 0.155 |
COSMIC
| Number Of Residues | 227 |
| Number Of SNVs | 5 |
| Number Of Permutations | 841 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.3 |
| p-value | 0.231 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.307 |
| p-value | 0.59 |