General Structure Information
| PDB ID | 2qxi |
| HGNC Gene Label(s) | KLK7 |
| Structure Name | high resolution structure of human kallikrein 7 in complex with suc-ala-ala-pro-phe-chloromethylketone |
| Resolution | 1.0Å |
| Reference | AUTH M.DEBELA,P.HESS,V.MAGDOLEN,N.M.SCHECHTER,T.STEINER,AUTH 2 R.HUBER,W.BODE,P.GOETTIGTITL CHYMOTRYPTIC SPECIFICITY DETERMINANTS IN THE 1.0 ATITL 2 STRUCTURE OF THE ZINC-INHIBITED HUMAN TISSUETITL 3 KALLIKREIN 7.REF PROC.NATL.ACAD.SCI.USA V. 104 16086 2007REFN ISSN 0027-8424PMID 17909180DOI 10.1073/PNAS.0707811104 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 221 |
| Number Of SNVs | 69 |
| Number Of Permutations | 21233 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.055 |
| p-value | 0.218 |
COSMIC
| Number Of Residues | 221 |
| Number Of SNVs | 7 |
| Number Of Permutations | 987 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.429 |
| p-value | 0.505 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 69 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.13 |
| p-value | 0.726 |