General Structure Information
| PDB ID | 2ob4 |
| HGNC Gene Label(s) | CDC34 |
| Structure Name | human ubiquitin-conjugating enzyme cdc34 |
| Resolution | 2.4Å |
| Reference | AUTH Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,AUTH 2 G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,AUTH 3 C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANONTITL A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASETITL 2 STRUCTURE-FUNCTION SCREEN.REF MOL CELL PROTEOMICS V. 11 329 2012REFNPMID 22496338DOI 10.1074/MCP.O111.013706 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 157 |
| Number Of SNVs | 20 |
| Number Of Permutations | 2394 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.2 |
| p-value | 0.085 |
COSMIC
| Number Of Residues | 157 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 20 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.77 |
| p-value | 0.001 |