General Structure Information
| PDB ID | 2pf6 |
| HGNC Gene Label(s) | BCAM |
| Structure Name | lutheran glycoprotein, n-terminal domains 1 and 2 |
| Resolution | 2.2Å |
| Reference | AUTH T.J.MANKELOW,N.BURTON,F.O.STEFANSDOTTIR,F.A.SPRING,AUTH 2 S.F.PARSONS,J.S.PEDERSEN,C.L.OLIVEIRA,D.LAMMIE,T.WESS,AUTH 3 N.MOHANDAS,J.A.CHASIS,R.L.BRADY,D.J.ANSTEETITL THE LAMININ 511/521-BINDING SITE ON THE LUTHERAN BLOOD GROUPTITL 2 GLYCOPROTEIN IS LOCATED AT THE FLEXIBLE JUNCTION OF IGTITL 3 DOMAINS 2 AND 3.REF BLOOD V. 110 3398 2007REFN ISSN 0006-4971PMID 17638854DOI 10.1182/BLOOD-2007-06-094748 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 231 |
| Number Of SNVs | 72 |
| Number Of Permutations | 47885 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.072 |
| p-value | 0.444 |
COSMIC
| Number Of Residues | 231 |
| Number Of SNVs | 4 |
| Number Of Permutations | 340 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.167 |
| p-value | 0.061 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 72 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.492 |
| p-value | 0.01 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
