General Structure Information
| PDB ID | 2x2r |
| HGNC Gene Label(s) | KIF11 |
| Structure Name | crystal structure of human kinesin eg5 in complex with (r)-2-amino-3-((4-chlorophenyl)diphenylmethylthio)propanoic acid |
| Resolution | 2.2Å |
| Reference | AUTH H.Y.K.KAAN,J.WEISS,D.MENGER,V.ULAGANATHAN,K.TKOCZ,C.LAGGNER,AUTH 2 F.POPOWYCZ,B.JOSEPH,F.KOZIELSKITITL STRUCTURE-ACTIVITY RELATIONSHIP AND MULTIDRUG RESISTANCETITL 2 STUDY OF NEW S-TRITYL-L-CYSTEINE DERIVATIVES AS INHIBITORSTITL 3 OF EG5.REF J.MED.CHEM. V. 54 1576 2011REFN ISSN 0022-2623PMID 21344920DOI 10.1021/JM100991M |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 331 |
| Number Of SNVs | 37 |
| Number Of Permutations | 27166 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.305 |
| p-value | 0.415 |