General Structure Information
| PDB ID | 2lqn |
| HGNC Gene Label(s) | CRKL |
| Structure Name | solution structure of crkl |
| Resolution | -1.0Å |
| Reference | AUTH W.JANKOWSKI,T.SALEH,M.T.PAI,G.SRIRAM,R.B.BIRGE,C.G.KALODIMOSTITL DOMAIN ORGANIZATION DIFFERENCES EXPLAIN BCR-ABLS PREFERENCETITL 2 FOR CRKL OVER CRKII.REF NAT.CHEM.BIOL. V. 8 590 2012REFN ISSN 1552-4450PMID 22581121DOI 10.1038/NCHEMBIO.954 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 303 |
| Number Of SNVs | 52 |
| Number Of Permutations | 12188 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.067 |
| p-value | 0.278 |
COSMIC
| Number Of Residues | 303 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2617 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.067 |
| p-value | 0.639 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 52 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | -0.265 |
| p-value | 0.424 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
