General Structure Information
| PDB ID | 3gro |
| HGNC Gene Label(s) | PPT1 |
| Structure Name | human palmitoyl-protein thioesterase 1 |
| Resolution | 2.53Å |
| Reference | AUTH E.DOBROVETSKY,A.SEITOVA,Y.TONG,W.TEMPEL,A.DONG,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,D.COSSAR,H.PARKTITL HUMAN PALMITOYL-PROTEIN THIOESTERASE 1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 268 |
| Number Of SNVs | 68 |
| Number Of Permutations | 7443 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.038 |
| p-value | 0.127 |
ClinVar
| Number Of Residues | 268 |
| Number Of SNVs | 27 |
| Number Of Permutations | 3289 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.057 |
| p-value | 0.022 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of ClinVar SNVs | 24 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.067 |
| p-value | 0.003 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
