General Structure Information
| PDB ID | 1ls6 |
| HGNC Gene Label(s) | SULT1A1 |
| Structure Name | human sult1a1 complexed with pap and p-nitrophenol |
| Resolution | 1.9Å |
| Reference | AUTH N.U.GAMAGE,R.G.DUGGLEBY,A.C.BARNETT,M.TRESILLIAN,AUTH 2 C.F.LATHAM,N.E.LIYOU,M.E.MCMANUS,J.L.MARTINTITL STRUCTURE OF A HUMAN CARCINOGEN-CONVERTING ENZYME,TITL 2 SULT1A1. STRUCTURAL AND KINETIC IMPLICATIONS OFTITL 3 SUBSTRATE INHIBITION.REF J.BIOL.CHEM. V. 278 7655 2003REFN ISSN 0021-9258PMID 12471039DOI 10.1074/JBC.M207246200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 288 |
| Number Of SNVs | 68 |
| Number Of Permutations | 6707 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.114 |
| p-value | 0.0 |
COSMIC
| Number Of Residues | 288 |
| Number Of SNVs | 10 |
| Number Of Permutations | 2043 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.089 |
| p-value | 0.692 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.062 |
| p-value | 0.657 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
