4ICK.B | NUDT2

PDB ID	4ick
HGNC Gene Label(s)	NUDT2
Structure Name	crystal structure of human ap4a hydrolase e58a mutant
Resolution	2.1Å
Reference	AUTH H.GE,X.CHEN,W.YANG,L.NIU,M.TENGTITL CRYSTAL STRUCTURE OF WILD-TYPE AND MUTANT HUMAN AP4ATITL 2 HYDROLASE.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 432 16 2013REFN ISSN 0006-291XPMID 23384440DOI 10.1016/J.BBRC.2013.01.095

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
9:34339053		C>R	B:6	(-4.51, 46.56, -12.50)
9:34339065	COSM3907000	I>V	B:10	(7.55, 47.36, -8.63)
9:34339072	COSM1108442	R>Q	B:12	(15.31, 48.46, -5.77)
9:34339083		I>V	B:16	(24.81, 46.10, -1.05)
9:34339104	rs141924472	A>S	B:23	(16.57, 45.09, 1.41)
9:34339126	rs201292035	Q>R	B:30	(3.82, 62.22, -7.25)
9:34339138		G>D	B:34	(-4.55, 66.63, -7.58)
9:34339149	rs373393372	W>R	B:38	(3.85, 59.45, -3.95)
9:34339155		P>S	B:40	(2.01, 51.50, -6.97)
9:34343133		P>S	B:47	(-11.60, 45.47, -23.28)
9:34343141		E>D	B:49	(-6.55, 43.46, -20.93)
9:34343168		E>D	B:58	(0.62, 49.82, -16.73)
9:34343185		G>V	B:64	(9.00, 51.72, -18.33)
9:34343188		I>R	B:65	(9.27, 48.65, -16.24)
9:34343193	rs150256259	A>T	B:67	(8.35, 42.20, -19.19)
9:34343212		I>T	B:73	(6.42, 37.07, -7.10)
9:34343224		K>R	B:77	(-3.75, 38.39, -5.89)
9:34343239		Y>F	B:82	(-10.62, 52.47, -2.76)
9:34343244		A>T	B:84	(-12.85, 57.56, -3.83)
9:34343245		A>G	B:84	(-12.85, 57.56, -3.83)
9:34343252		N>K	B:86	(-18.06, 58.51, -3.22)
9:34343361	rs147348519	C>R	B:123	(3.66, 53.29, 4.02)
9:34343365		Q>P	B:124	(5.28, 57.66, 5.70)
9:34343376		F>I	B:128	(-5.02, 55.43, 1.52)
9:34343395		A>V	B:134	(-0.35, 45.73, 0.75)
9:34343406		G>R	B:138	(4.46, 41.86, 0.78)
9:34343407		G>E	B:138	(4.46, 41.86, 0.78)
9:34343434		A>V	B:147	(13.20, 31.96, 5.32)

4ICK.B | NUDT2.