3ENM.C | MAP2K6

General Structure Information

PDB ID 3enm
HGNC Gene Label(s) MAP2K6
Structure Name the structure of the map2k mek6 reveals an autoinhibitory dimer
Resolution 2.35Å
Reference AUTH X.MIN,R.AKELLA,H.HE,J.M.HUMPHREYS,S.E.TSUTAKAWA,S.J.LEE,AUTH 2 J.A.TAINER,M.H.COBB,E.J.GOLDSMITHTITL THE STRUCTURE OF THE MAP2K MEK6 REVEALS AN AUTOINHIBITORYTITL 2 DIMERREF STRUCTURE V. 17 96 2009REFN ISSN 0969-2126PMID 19141286DOI 10.1016/J.STR.2008.11.007

Variant Set Distributions

ExAC Variants

Number Of Residues 263
Number Of SNVs 36
Number Of Permutations 4842
Optimal Distance Threshold 8.0
K Statistic 0.044
p-value 0.748

Mapped Variants

[+] ExAC Missense Variants