General Structure Information
| PDB ID | 3ii6 |
| HGNC Gene Label(s) | LIG4 |
| Structure Name | structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. |
| Resolution | 2.4Å |
| Reference | AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 256 |
| Number Of SNVs | 67 |
| Number Of Permutations | 16299 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.085 |
| p-value | 0.973 |
COSMIC
| Number Of Residues | 256 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.152 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
