General Structure Information
| PDB ID | 1xa6 |
| HGNC Gene Label(s) | CHN2 |
| Structure Name | crystal structure of the human beta2-chimaerin |
| Resolution | 3.2Å |
| Reference | AUTH B.CANAGARAJAH,F.C.LESKOW,J.Y.HO,H.MISCHAK,AUTH 2 L.F.SAIDI,M.G.KAZANIETZ,J.H.HURLEYTITL STRUCTURAL MECHANISM FOR LIPID ACTIVATION OF THETITL 2 RAC-SPECIFIC GAP, BETA2-CHIMAERIN.REF CELL(CAMBRIDGE,MASS.) V. 119 407 2004REFN ISSN 0092-8674PMID 15507211DOI 10.1016/J.CELL.2004.10.012 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 399 |
| Number Of SNVs | 93 |
| Number Of Permutations | 26984 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.184 |
| p-value | 0.265 |
COSMIC
| Number Of Residues | 399 |
| Number Of SNVs | 3 |
| Number Of Permutations | 288 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.333 |
| p-value | 0.675 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 93 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.08 |
| p-value | 0.868 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
