2GS3.A | GPX4

General Structure Information

PDB ID 2gs3
HGNC Gene Label(s) GPX4
Structure Name crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(gpx4)
Resolution 1.9Å
Reference AUTH C.JOHANSSON,K.L.KAVANAGH,A.ROJKOVA,O.GILEADI,F.VON DELFT,AUTH 2 C.ARROWSMITH,J.WEIGELT,M.SUNDSTROM,A.EDWARDS,U.OPPERMANN,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF THE SELENOCYSTEINE TO GLYCINE MUTANT OFTITL 2 HUMAN GLUTATHIONE PEROXIDASE 4(GPX4)REF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 162
Number Of SNVs 59
Number Of Permutations 2999
Optimal Distance Threshold 12.0
K Statistic 0.14
p-value 0.022

Mapped Variants

[+] ExAC Missense Variants