General Structure Information
| PDB ID | 2ger |
| HGNC Gene Label(s) | PYCR1 |
| Structure Name | crystal structure and oxidative mechanism of human pyrroline-5- carboxylate reductase |
| Resolution | 3.1Å |
| Reference | AUTH Z.MENG,Z.LOU,Z.LIU,M.LI,X.ZHAO,M.BARTLAM,Z.RAOTITL CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE REDUCTASEREF J.MOL.BIOL. V. 359 1364 2006REFN ISSN 0022-2836PMID 16730026DOI 10.1016/J.JMB.2006.04.053 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 275 |
| Number Of SNVs | 76 |
| Number Of Permutations | 45486 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.032 |
| p-value | 0.834 |
ClinVar
| Number Of Residues | 275 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2617 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.333 |
| p-value | 0.396 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of ClinVar SNVs | 6 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.168 |
| p-value | 0.408 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
