General Structure Information
| PDB ID | 3c59 |
| HGNC Gene Label(s) | GLP1R |
| Structure Name | crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain |
| Resolution | 2.3Å |
| Reference | AUTH S.RUNGE,H.THOGERSEN,K.MADSEN,J.LAU,R.RUDOLPHTITL CRYSTAL STRUCTURE OF THE LIGAND-BOUND GLUCAGON-LIKETITL 2 PEPTIDE-1 RECEPTOR EXTRACELLULAR DOMAINREF J.BIOL.CHEM. V. 283 11340 2008REFN ISSN 0021-9258PMID 18287102DOI 10.1074/JBC.M708740200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 103 |
| Number Of SNVs | 20 |
| Number Of Permutations | 2001 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.026 |
| p-value | 1.0 |
COSMIC
| Number Of Residues | 103 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

