General Structure Information
| PDB ID | 3g81 |
| HGNC Gene Label(s) | SFTPD |
| Structure Name | crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein d in complex with alpha methyl mannoside |
| Resolution | 1.8Å |
| Reference | AUTH E.CROUCH,K.HARTSHORN,T.HORLACHER,B.MCDONALD,K.SMITH,AUTH 2 T.CAFARELLA,B.SEATON,P.H.SEEBERGER,J.HEADTITL RECOGNITION OF MANNOSYLATED LIGANDS AND INFLUENZA A VIRUS BYTITL 2 HUMAN SURFACTANT PROTEIN D: CONTRIBUTIONS OF AN EXTENDEDTITL 3 SITE AND RESIDUE 343.REF BIOCHEMISTRY V. 48 3335 2009REFN ISSN 0006-2960PMID 19249874DOI 10.1021/BI8022703 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 150 |
| Number Of SNVs | 40 |
| Number Of Permutations | 13031 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.401 |
| p-value | 0.177 |
COSMIC
| Number Of Residues | 150 |
| Number Of SNVs | 3 |
| Number Of Permutations | 109 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.71 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 40 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.231 |
| p-value | 0.834 |