General Structure Information
| PDB ID | 1b98 |
| HGNC Gene Label(s) | NTF4 |
| Structure Name | neurotrophin 4 (homodimer) |
| Resolution | 2.75Å |
| Reference | AUTH R.C.ROBINSON,C.RADZIEJEWSKI,G.SPRAGGON,J.GREENWALD,AUTH 2 M.R.KOSTURA,L.D.BURTNICK,D.I.STUART,S.CHOE,AUTH 3 E.Y.JONESTITL THE STRUCTURES OF THE NEUROTROPHIN 4 HOMODIMER ANDTITL 2 THE BRAIN-DERIVED NEUROTROPHIC FACTOR/NEUROTROPHINTITL 3 4 HETERODIMER REVEAL A COMMON TRK-BINDING SITE.REF PROTEIN SCI. V. 8 2589 1999REFN ISSN 0961-8368PMID 10631974 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 113 |
| Number Of SNVs | 42 |
| Number Of Permutations | 6622 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.426 |
| p-value | 0.768 |
ClinVar
COSMIC
| Number Of Residues | 113 |
| Number Of SNVs | 3 |
| Number Of Permutations | 167 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.667 |
| p-value | 0.643 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
Cosmic vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.275 |
| p-value | 0.862 |