General Structure Information
| PDB ID | 2dm0 |
| HGNC Gene Label(s) | TXK |
| Structure Name | solution structure of the sh2 domain of human tyrosine- protein kinase txk |
| Resolution | -1.0Å |
| Reference | AUTH H.ENDO,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMANTITL 2 TYROSINE-PROTEIN KINASE TXKREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 112 |
| Number Of SNVs | 36 |
| Number Of Permutations | 5342 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.149 |
| p-value | 0.541 |
COSMIC
| Number Of Residues | 112 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.33 |
| p-value | 0.824 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
