General Structure Information
| PDB ID | 2v40 |
| HGNC Gene Label(s) | ADSS |
| Structure Name | human adenylosuccinate synthetase isozyme 2 in complex with gdp |
| Resolution | 1.9Å |
| Reference | AUTH M.WELIN,M.MOCHE,C.ARROWSMITH,H.BERGLUND,R.BUSAM,AUTH 2 R.COLLINS,L.G.DAHLGREN,A.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,B.M.HALLBERG,AUTH 4 L.HOLMBERG-SCHIAVONE,I.JOHANSSON,A.KALLAS,AUTH 5 T.KARLBERG,T.KOTENYOVA,L.LEHTIO,T.NYMAN,D.OGG,AUTH 6 C.PERSSON,J.SAGEMARK,P.STENMARK,M.SUNDSTROM,AUTH 7 A.G.THORSELL,S.VAN-DEN-BERG,J.WEIGELT,P.NORDLUNDTITL HUMAN ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 INTITL 2 COMPLEX WITH GDPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 419 |
| Number Of SNVs | 63 |
| Number Of Permutations | 11870 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.264 |
| p-value | 0.057 |
COSMIC
| Number Of Residues | 419 |
| Number Of SNVs | 3 |
| Number Of Permutations | 204 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.667 |
| p-value | 0.243 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
