4IB4.A | HTR2B

General Structure Information

PDB ID 4ib4
HGNC Gene Label(s) HTR2B
Structure Name crystal structure of the chimeric protein of 5-ht2b-bril in complex with ergotamine
Resolution 2.7Å
Reference AUTH D.WACKER,C.WANG,V.KATRITCH,G.W.HAN,X.P.HUANG,E.VARDY,AUTH 2 J.D.MCCORVY,Y.JIANG,M.CHU,F.Y.SIU,W.LIU,H.E.XU,V.CHEREZOV,AUTH 3 B.L.ROTH,R.C.STEVENSTITL STRUCTURAL FEATURES FOR FUNCTIONAL SELECTIVITY AT SEROTONINTITL 2 RECEPTORS.REF SCIENCE V. 340 615 2013REFN ISSN 0036-8075PMID 23519215DOI 10.1126/SCIENCE.1232808

Variant Set Distributions

ExAC Variants

Number Of Residues 285
Number Of SNVs 73
Number Of Permutations 18318
Optimal Distance Threshold 9.0
K Statistic 0.047
p-value 0.773

Mapped Variants

[+] ExAC Missense Variants