General Structure Information
| PDB ID | 1ej5 |
| HGNC Gene Label(s) | WAS |
| Structure Name | solution structure of the autoinhibited conformation of wasp |
| Resolution | -1.0Å |
| Reference | AUTH A.S.KIM,L.T.KAKALIS,N.ABDUL-MANAN,G.A.LIU,M.K.ROSENTITL AUTOINHIBITION AND ACTIVATION MECHANISMS OF THETITL 2 WISKOTT-ALDRICH SYNDROME PROTEIN.REF NATURE V. 404 151 2000REFN ISSN 0028-0836PMID 10724160DOI 10.1038/35010088 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 107 |
| Number Of SNVs | 10 |
| Number Of Permutations | 6131 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.267 |
| p-value | 0.067 |
ClinVar
| Number Of Residues | 107 |
| Number Of SNVs | 4 |
| Number Of Permutations | 944 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 0.274 |
COSMIC
| Number Of Residues | 107 |
| Number Of SNVs | 3 |
| Number Of Permutations | 109 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.333 |
| p-value | 0.981 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 10 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.289 |
| p-value | 0.14 |
Cosmic vs. ExAC
