General Structure Information
| PDB ID | 1ncn |
| HGNC Gene Label(s) | CD86 |
| Structure Name | the receptor-binding domain of human b7-2 |
| Resolution | 2.7Å |
| Reference | AUTH X.ZHANG,J.D.SCHWARTZ,S.C.ALMO,S.G.NATHENSONTITL CRYSTAL STRUCTURE OF THE RECEPTOR-BINDING DOMAINTITL 2 OF HUMAN B7-2: INSIGHTS INTO ORGANIZATION ANDTITL 3 SIGNALINGREF PROC.NATL.ACAD.SCI.USA V. 100 2586 2003REFN ISSN 0027-8424PMID 12606712DOI 10.1073/PNAS.252771499 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 109 |
| Number Of SNVs | 17 |
| Number Of Permutations | 6427 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.066 |
| p-value | 0.284 |
COSMIC
| Number Of Residues | 109 |
| Number Of SNVs | 4 |
| Number Of Permutations | 961 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.5 |
| p-value | 0.375 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 17 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.39 |
| p-value | 0.105 |