General Structure Information
| PDB ID | 2w2j |
| HGNC Gene Label(s) | CA8 |
| Structure Name | crystal structure of the human carbonic anhydrase related protein viii |
| Resolution | 1.6Å |
| Reference | AUTH S.S.PICAUD,J.R.C.MUNIZ,A.KRAMM,E.S.PILKA,G.KOCHAN,AUTH 2 U.OPPERMANN,W.W.YUETITL CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE-TITL 2 RELATED PROTEIN VIII REVEALS THE BASIS FORTITL 3 CATALYTIC SILENCING.REF PROTEINS V. 76 507 2009REFN ISSN 0887-3585PMID 19360879DOI 10.1002/PROT.22411 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 268 |
| Number Of SNVs | 49 |
| Number Of Permutations | 6941 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.129 |
| p-value | 0.068 |
COSMIC
| Number Of Residues | 268 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.548 |
| p-value | 0.255 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
