General Structure Information
| PDB ID | 2wjx |
| HGNC Gene Label(s) | GRIA2 |
| Structure Name | crystal structure of the human ionotropic glutamate receptor glur2 atd region at 4.1 a resolution |
| Resolution | 4.1Å |
| Reference | AUTH A.CLAYTON,C.SIEBOLD,R.J.C.GILBERT,G.C.SUTTON,AUTH 2 K.HARLOS,R.A.J.MCILHINNEY,E.Y.JONES,A.R.ARICESCUTITL CRYSTAL STRUCTURE OF THE GLUR2 AMINO-TERMINALTITL 2 DOMAIN PROVIDES INSIGHTS INTO THE ARCHITECTURE ANDTITL 3 ASSEMBLY OF IONOTROPIC GLUTAMATE RECEPTORS.REF J.MOL.BIOL. V. 392 1125 2009REFN ISSN 0022-2836PMID 19651138DOI 10.1016/J.JMB.2009.07.082 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 59 |
| Number Of Permutations | 31919 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.372 |
| p-value | 0.334 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 11 |
| Number Of Permutations | 11114 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.145 |
| p-value | 0.242 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | -0.022 |
| p-value | 0.85 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
