General Structure Information
| PDB ID | 2c5d |
| HGNC Gene Label(s) | AXL |
| Structure Name | structure of a minimal gas6-axl complex |
| Resolution | 3.3Å |
| Reference | AUTH T.SASAKI,P.G.KNYAZEV,N.J.CLOUT,Y.CHEBURKIN,AUTH 2 W.GOEHRING,A.ULLRICH,R.TIMPL,E.HOHENESTERTITL STRUCTURAL BASIS FOR GAS6-AXL SIGNALLING.REF EMBO J. V. 25 80 2006REFN ISSN 0261-4189PMID 16362042DOI 10.1038/SJ.EMBOJ.7600912 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 192 |
| Number Of SNVs | 53 |
| Number Of Permutations | 16999 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.289 |
COSMIC
| Number Of Residues | 192 |
| Number Of SNVs | 3 |
| Number Of Permutations | 169 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.667 |
| p-value | 0.52 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.295 |
| p-value | 0.947 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
