3KFD.J | TGFBR1

General Structure Information

PDB ID 3kfd
HGNC Gene Label(s) TGFBR1
Structure Name ternary complex of tgf-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily
Resolution 3.0Å
Reference AUTH S.RADAEV,Z.ZOU,T.HUANG,E.M.LAFER,A.P.HINCK,P.D.SUNTITL TERNARY COMPLEX OF TRANSFORMING GROWTH FACTOR-BETA1 REVEALSTITL 2 ISOFORM-SPECIFIC LIGAND RECOGNITION AND RECEPTORTITL 3 RECRUITMENT IN THE SUPERFAMILY.REF J.BIOL.CHEM. V. 285 14806 2010REFN ISSN 0021-9258PMID 20207738DOI 10.1074/JBC.M109.079921

Variant Set Distributions

ExAC Variants

Number Of Residues 70
Number Of SNVs 10
Number Of Permutations 2166
Optimal Distance Threshold 10.0
K Statistic 0.244
p-value 0.667

Mapped Variants

[+] ExAC Missense Variants