3K72.C | ITGAX

General Structure Information

PDB ID	3k72
HGNC Gene Label(s)	ITGAX
Structure Name	structure of integrin alphax beta2
Resolution	3.7Å
Reference	AUTH C.XIE,J.ZHU,X.CHEN,L.MI,N.NISHIDA,T.A.SPRINGERTITL STRUCTURE OF AN INTEGRIN WITH AN ALPHAI DOMAIN,TITL 2 COMPLEMENT RECEPTOR TYPE 4.REF EMBO J. V. 29 666 2010REFN ISSN 0261-4189PMID 20033057DOI 10.1038/EMBOJ.2009.367

Variant Set Distributions

ExAC Variants

Number Of Residues	882
Number Of SNVs	252
Number Of Permutations	91737
Optimal Distance Threshold	16.0
K Statistic	0.066
p-value	0.77

COSMIC

Number Of Residues	882
Number Of SNVs	22
Number Of Permutations	12391
Optimal Distance Threshold	4.0
K Statistic	0.004
p-value	0.461

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs	252
Number Of COSMIC SNVs	23
Optimal Distance Threshold	18.0
K Statistic	0.059
p-value	0.601

Mapped Variants

[+] ExAC Missense Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
16:31367238		N>S	C:2	(34.39, 57.03, 94.42)
16:31367241		L>S	C:3	(36.92, 57.64, 98.31)
16:31367245	rs369455265	D>E	C:4	(38.45, 62.98, 97.97)
16:31367247	COSM1518923	T>R	C:5	(42.51, 61.85, 98.20)
16:31367255		L>V	C:8	(39.29, 66.75, 102.55)
16:31367261		A>T	C:10	(39.49, 68.84, 108.73)
16:31367267	rs372481940	R>C	C:12	(43.60, 69.77, 113.02)
16:31367268		R>H	C:12	(43.60, 69.77, 113.02)
16:31367270		V>M	C:13	(39.46, 69.42, 118.09)
16:31367279		A>T	C:16	(42.25, 64.19, 124.24)
16:31367292		D>G	C:20	(38.18, 57.57, 119.84)
16:31367295		S>N	C:21	(33.80, 57.83, 118.55)
16:31367304	rs138486533	Q>L	C:24	(26.75, 60.35, 110.05)
16:31367305		Q>H	C:24	(26.75, 60.35, 110.05)
16:31367307	rs201047975	Y>C	C:25	(22.79, 64.34, 114.18)
16:31367318	rs2230424	W>R	C:29	(25.47, 69.72, 112.54)
16:31367960		A>V	C:34	(35.82, 62.86, 124.04)
16:31367962		P>S	C:35	(36.04, 60.00, 126.08)
16:31367990	rs375890125	T>M	C:44	(32.68, 63.56, 131.94)
16:31367992	rs369769040	G>C	C:45	(34.05, 64.59, 128.68)
16:31367996	rs373555641	G>D	C:46	(32.53, 65.14, 125.65)
16:31367998	rs200902675	L>I	C:47	(29.98, 65.42, 122.97)
16:31368014		Y>C	C:52	(31.10, 71.63, 104.51)
16:31368019		T>S	C:54	(32.05, 76.52, 109.21)
16:31368020		T>S	C:54	(32.05, 76.52, 109.21)
16:31368037		I>V	C:60	(27.09, 69.76, 122.99)
16:31368040	rs143407533	G>C	C:61	(25.17, 70.89, 125.67)
16:31368354		P>T	C:65	(24.49, 64.35, 136.09)
16:31368358		P>L	C:66	(26.10, 65.11, 139.89)
16:31368363	COSM970202	A>P	C:68	(27.74, 60.82, 136.78)
16:31368364	rs370805911	A>V	C:68	(27.74, 60.82, 136.78)
16:31368366	rs373622931	V>M	C:69	(31.43, 59.85, 138.08)
16:31368418		L>R	C:86	(22.30, 61.30, 118.78)
16:31368580	COSM970204	G>S	C:90	(28.56, 56.75, 129.43)
16:31368589		V>M	C:93	(29.06, 55.41, 135.69)
16:31368593		H>R	C:94	(32.47, 55.45, 138.45)
16:31368608		R>K	C:99	(31.18, 46.94, 149.73)
16:31368622	rs141436259	T>A	C:104	(25.95, 51.96, 135.34)
16:31368625	rs150827519	G>R	C:105	(25.73, 53.84, 132.79)
16:31368643	rs201621258	G>R	C:111	(17.43, 66.71, 119.17)
16:31368681		R>S	C:123	(20.16, 58.02, 141.82)
16:31371024		C>F	C:126	(23.49, 50.30, 145.71)
16:31373186	rs375953997 COSM970207	E>K	C:329	(23.03, 40.24, 138.93)
16:31373225		T>A	C:342	(14.89, 49.90, 116.46)
16:31373228		P>S	C:343	(11.77, 50.60, 114.69)
16:31373229	rs142750657	P>L	C:343	(11.77, 50.60, 114.69)
16:31373405		V>I	C:347	(19.14, 48.89, 121.93)
16:31373414	COSM703163	A>S	C:350	(25.30, 44.79, 128.65)
16:31373415		A>V	C:350	(25.30, 44.79, 128.65)
16:31373417		V>M	C:351	(28.99, 43.64, 129.56)
16:31373426		F>L	C:354	(24.12, 38.19, 134.98)
16:31373433	rs200606612	W>S	C:356	(31.48, 40.50, 133.68)
16:31373457	rs138501712	P>L	C:364	(10.08, 50.79, 124.78)
16:31373462	rs375007025	N>D	C:366	(7.21, 56.07, 127.87)
16:31373469		S>I	C:368	(8.58, 49.26, 130.52)
16:31373496	rs138866008	E>A	C:377	(18.81, 26.73, 131.31)
16:31373517		S>Y	C:384	(31.65, 37.13, 126.54)
16:31373525		G>C	C:387	(27.54, 43.50, 123.75)
16:31373943	COSM471671	E>K	C:391	(23.80, 46.46, 114.31)
16:31373952		L>F	C:394	(15.09, 45.48, 109.12)
16:31373961		G>R	C:397	(9.55, 41.60, 109.09)
16:31373962		G>E	C:397	(9.55, 41.60, 109.09)
16:31373991	rs201384441 COSM3509163 COSM2156423	R>C	C:407	(36.58, 36.79, 126.38)
16:31373992	COSM1255041	R>H	C:407	(36.58, 36.79, 126.38)
16:31373995		Y>S	C:408	(31.88, 31.07, 123.58)
16:31374006	rs554674355	G>R	C:412	(34.57, 34.10, 119.66)
16:31374010	rs200497327	K>M	C:413	(29.96, 33.00, 119.88)
16:31374012	rs376618435 COSM1709094	A>S	C:414	(28.19, 35.62, 117.24)
16:31374016		V>A	C:415	(24.61, 35.66, 119.17)
16:31374018		I>V	C:416	(21.62, 36.36, 115.86)
16:31374025	rs139553693	T>S	C:418	(14.30, 36.76, 117.71)
16:31374057	rs559233176	E>K	C:429	(25.09, 30.61, 117.72)
16:31374064		T>M	C:431	(31.90, 29.59, 116.88)
16:31374259		G>S	C:436	(41.88, 35.63, 120.27)
16:31374271		G>R	C:440	(32.94, 40.21, 117.68)
16:31374289		V>M	C:446	(25.04, 45.22, 104.69)
16:31374295		V>I	C:448	(23.76, 43.63, 98.51)
16:31374307	rs149061469	G>S	C:452	(15.62, 46.83, 102.79)
16:31374313	COSM1609232	T>A	C:454	(19.27, 42.93, 106.15)
16:31374314		T>I	C:454	(19.27, 42.93, 106.15)
16:31374316	COSM3772203	D>N	C:455	(20.72, 40.53, 102.54)
16:31374323		V>A	C:457	(26.23, 40.35, 108.85)
16:31374331		G>R	C:460	(35.33, 41.06, 113.86)
16:31374349	COSM1255039	E>K	C:466	(47.38, 31.57, 109.11)
16:31374359	rs151306268	R>Q	C:469	(49.94, 38.64, 113.22)
16:31374395		G>V	C:481	(15.88, 29.30, 109.83)
16:31374486		W>R	C:482	(14.53, 30.43, 114.38)
16:31374490		R>T	C:483	(17.33, 24.95, 115.74)
16:31374500	COSM703161	W>C	C:486	(25.15, 29.71, 106.54)
16:31374516	rs369681895	Y>H	C:492	(38.17, 34.93, 104.82)
16:31374525		Q>K	C:495	(45.89, 43.27, 103.49)
16:31374532		H>R	C:497	(50.71, 44.94, 107.30)
16:31374535	rs2230429	P>R	C:498	(51.39, 42.13, 109.68)
16:31374543	rs538457810 COSM3664775	R>C	C:501	(44.91, 47.31, 114.80)
16:31374544	COSM1293585	R>H	C:501	(44.91, 47.31, 114.80)
16:31374549		G>W	C:503	(38.11, 45.39, 111.96)
16:31374552		A>T	C:504	(38.07, 47.79, 114.15)
16:31374559		L>P	C:506	(32.65, 48.25, 110.10)
16:31374568	COSM557691	L>P	C:509	(28.87, 54.02, 102.25)
16:31374571		G>V	C:510	(26.36, 52.25, 99.84)
16:31374600		V>M	C:520	(31.48, 48.48, 102.61)
16:31374616		P>Q	C:525	(44.14, 51.48, 112.95)
16:31374624	rs17853815	E>K	C:528	(51.41, 51.51, 107.41)
16:31374631	rs149382567	N>S	C:530	(50.74, 52.61, 114.35)
16:31374633	rs144712449	R>W	C:531	(51.31, 55.88, 110.26)
16:31374634	rs201067451 COSM970212 COSM1377638	R>Q	C:531	(51.31, 55.88, 110.26)
16:31374675	rs189592567	I>V	C:545	(32.06, 40.50, 99.63)
16:31374691	rs372608623	S>N	C:550	(38.97, 49.43, 95.03)
16:31382411		A>T	C:554	(46.06, 55.37, 104.07)
16:31382412	rs148255116	A>V	C:554	(46.06, 55.37, 104.07)
16:31382415	COSM703160	G>A	C:555	(48.27, 57.40, 106.18)
16:31382420		Q>E	C:557	(47.05, 59.77, 101.32)
16:31382429	rs201604889	S>P	C:560	(51.05, 65.02, 108.09)
16:31382430		S>F	C:560	(51.05, 65.02, 108.09)
16:31382440		Q>H	C:563	(49.86, 57.14, 115.61)
16:31382460		S>T	C:570	(30.01, 56.26, 110.29)
16:31382477		T>A	C:576	(28.39, 68.33, 102.07)
16:31382478		T>S	C:576	(28.39, 68.33, 102.07)
16:31382481	rs372238101	Q>R	C:577	(24.04, 69.97, 101.37)
16:31382492	rs200451726 COSM1518916	V>M	C:581	(27.06, 59.66, 100.14)
16:31382496		D>G	C:582	(29.40, 61.93, 102.75)
16:31382507		G>R	C:586	(38.33, 58.65, 112.92)
16:31382508	COSM3957506	G>E	C:586	(38.33, 58.65, 112.92)
16:31382510	rs143688440	A>T	C:587	(41.31, 60.12, 114.40)
16:31382516		G>S	C:589	(42.46, 64.37, 117.16)
16:31382517	rs200052033	G>D	C:589	(42.46, 64.37, 117.16)
16:31382523	rs542150274	V>A	C:591	(37.61, 63.94, 112.14)
16:31382528		L>V	C:593	(34.53, 64.29, 106.02)
16:31382532		L>H	C:594	(36.34, 61.09, 102.79)
16:31382657		T>I	C:596	(31.42, 60.27, 97.03)
16:31382666		V>A	C:599	(30.94, 57.24, 88.99)
16:31382673		W>C	C:601	(28.53, 54.07, 83.86)
16:31382678		G>E	C:603	(28.16, 55.02, 75.41)
16:31382680	rs147141299	V>M	C:604	(29.96, 53.99, 72.02)
16:31382696	rs371940371	I>T	C:609	(28.68, 56.33, 55.98)
16:31382704	rs149696971	E>K	C:612	(31.94, 47.47, 51.73)
16:31382720		A>V	C:617	(40.21, 52.44, 45.59)
16:31382727		E>D	C:619	(44.03, 46.27, 42.59)
16:31382731		R>W	C:621	(46.11, 52.62, 36.76)
16:31382732	rs202093756	R>Q	C:621	(46.11, 52.62, 36.76)
16:31382736		E>D	C:622	(51.07, 53.55, 38.11)
16:31382768		S>Y	C:633	(33.55, 57.65, 60.49)
16:31382771		N>S	C:634	(29.48, 58.62, 62.75)
16:31382774		I>N	C:635	(31.91, 58.18, 66.36)
16:31382776		C>R	C:636	(28.27, 58.57, 68.78)
16:31382786		I>T	C:639	(25.80, 59.72, 79.39)
16:31382793		K>N	C:641	(23.80, 53.73, 84.63)
16:31382794		R>C	C:642	(19.96, 58.18, 85.07)
16:31382978	rs144399274	D>G	C:659	(42.31, 60.09, 70.93)
16:31382980		L>V	C:660	(40.22, 58.79, 66.68)
16:31382984		A>V	C:661	(43.34, 55.42, 65.50)
16:31382989	COSM3509174	D>N	C:663	(45.53, 50.17, 61.03)
16:31382998	COSM158644	R>C	C:666	(49.08, 47.38, 60.69)
16:31383008	rs200214510	P>L	C:669	(49.44, 53.68, 57.94)
16:31383010	rs371319485	R>C	C:670	(45.17, 50.11, 55.75)
16:31383011	rs529457963	R>H	C:670	(45.17, 50.11, 55.75)
16:31383014		A>V	C:671	(44.72, 55.86, 56.48)
16:31383021		F>L	C:673	(41.65, 60.96, 60.35)
16:31383024	COSM1679046	Q>H	C:674	(40.72, 65.80, 55.36)
16:31383037	rs377256876	R>W	C:679	(47.97, 56.73, 62.17)
16:31383056	rs200412395	R>Q	C:685	(33.92, 68.33, 70.54)
16:31383064	rs368436373 COSM3988449	G>R	C:688	(25.72, 64.22, 77.19)
16:31383079	rs141438842	C>R	C:693	(27.00, 62.47, 66.66)
16:31383083		E>G	C:694	(31.78, 64.36, 64.81)
16:31383100		L>F	C:700	(41.29, 55.16, 51.43)
16:31383103	rs61761300	P>A	C:701	(45.11, 55.00, 49.55)
16:31383104	rs200637041 COSM172251	P>L	C:701	(45.11, 55.00, 49.55)
16:31383702		C>R	C:703	(47.15, 52.07, 45.83)
16:31383717		V>M	C:708	(41.97, 40.84, 53.64)
16:31383736		R>H	C:714	(42.05, 53.08, 69.03)
16:31383743		N>K	C:716	(41.57, 57.41, 74.10)
16:31383748	COSM3402302	T>M	C:718	(38.95, 60.74, 78.86)
16:31383757		G>D	C:721	(39.29, 69.29, 82.99)
16:31383762	rs534386912	P>S	C:723	(35.77, 72.40, 84.24)
16:31383786	rs139559004	R>W	C:731	(37.63, 63.16, 90.85)
16:31383787	COSM3690964	R>Q	C:731	(37.63, 63.16, 90.85)
16:31383801	COSM4060455	A>T	C:736	(36.03, 49.67, 86.36)
16:31383804		D>N	C:737	(34.11, 47.60, 83.74)
16:31383810		Q>E	C:739	(35.82, 48.69, 77.80)
16:31383811		Q>R	C:739	(35.82, 48.69, 77.80)
16:31383817		Y>F	C:741	(41.30, 51.70, 74.50)
16:31383820		F>C	C:742	(34.94, 51.24, 72.75)
16:31383823		T>M	C:743	(37.29, 49.13, 67.76)
16:31383922	rs151251765	P>L	C:747	(34.95, 46.07, 55.46)
16:31383924		F>V	C:748	(38.35, 46.01, 52.39)
16:31383943		A>D	C:754	(37.47, 38.93, 37.13)
16:31383945	rs371564736	D>N	C:755	(34.47, 37.21, 37.10)
16:31383949	rs561228143	H>R	C:756	(31.70, 34.58, 40.51)
16:31383952	rs374096304	I>N	C:757	(29.25, 38.84, 41.21)
16:31383966		L>V	C:762	(26.45, 31.72, 54.43)
16:31383969		G>S	C:763	(24.11, 28.84, 56.70)
16:31383976	rs186307252	S>F	C:765	(21.75, 24.80, 62.26)
16:31383991	COSM1316437	G>D	C:770	(20.27, 16.27, 75.81)
16:31384578		S>F	C:773	(13.36, 20.27, 80.59)
16:31384592		S>G	C:778	(19.40, 22.64, 87.20)
16:31384599		L>R	C:780	(24.08, 26.89, 84.97)
16:31384610	COSM1679047	A>T	C:784	(25.37, 24.68, 71.84)
16:31384617		V>A	C:786	(26.61, 25.50, 65.89)
16:31384622		V>M	C:788	(27.78, 26.48, 59.43)
16:31384623		V>A	C:788	(27.78, 26.48, 59.43)
16:31384649	rs551919887 COSM3509180 COSM557684	G>R	C:797	(34.69, 37.49, 58.67)
16:31384667		S>P	C:803	(18.91, 35.91, 70.13)
16:31384676		A>T	C:806	(18.80, 38.41, 79.95)
16:31384680		G>E	C:807	(19.49, 35.12, 81.41)
16:31384683		L>Q	C:808	(21.66, 33.97, 78.83)
16:31384691		R>C	C:811	(31.06, 29.61, 80.10)
16:31384695		Y>S	C:812	(36.63, 30.13, 75.58)
16:31384697	rs373047580	V>M	C:813	(34.71, 26.37, 76.13)
16:31388135	rs138066479	R>C	C:823	(35.22, 24.93, 70.01)
16:31388144		H>Y	C:826	(40.53, 32.20, 68.71)
16:31388162	rs148620790	A>T	C:832	(25.01, 43.39, 73.88)
16:31388168	rs182689124	V>F	C:834	(19.49, 45.00, 71.45)
16:31388179	rs200663453	Q>H	C:837	(11.96, 45.86, 77.91)
16:31388180		G>S	C:838	(15.13, 41.95, 77.22)
16:31388184		T>I	C:839	(16.08, 40.85, 74.21)
16:31388211		H>R	C:848	(42.40, 33.44, 63.79)
16:31388219	COSM1324480	F>V	C:851	(33.64, 29.12, 56.01)
16:31388222		R>C	C:852	(38.46, 29.01, 51.39)
16:31388228		G>S	C:854	(31.24, 23.98, 50.98)
16:31388231	COSM401638	A>T	C:855	(32.54, 24.03, 53.88)
16:31388343		D>G	C:864	(26.34, 30.62, 81.82)
16:31388355	rs201039279	K>R	C:868	(16.80, 35.20, 90.05)
16:31388372	rs200290467	R>W	C:874	(8.06, 28.62, 75.18)
16:31388373		R>Q	C:874	(8.06, 28.62, 75.18)
16:31388378	rs565521371	L>I	C:876	(13.30, 32.58, 71.75)
16:31388379	rs539082671	L>P	C:876	(13.30, 32.58, 71.75)
16:31388391		N>S	C:880	(21.71, 36.25, 62.69)
16:31388507	rs373321354	N>D	C:885	(31.56, 41.49, 52.93)
16:31388509		N>K	C:885	(31.56, 41.49, 52.93)
16:31388527	rs201236234	S>R	C:891	(16.18, 37.22, 53.20)
16:31388553	COSM471673 COSM3672240	P>L	C:900	(9.99, 24.22, 76.99)
16:31388556		V>A	C:901	(10.84, 27.05, 80.96)
16:31388573		T>S	C:907	(9.17, 20.66, 98.33)
16:31390938		E>K	C:928	(-15.16, 5.32, 120.20)
16:31390953		M>V	C:933	(-2.83, 13.29, 116.63)
16:31391078		V>F	C:938	(5.67, 21.36, 105.15)
16:31391082		N>S	C:939	(9.51, 22.92, 104.68)
16:31391094		Q>P	C:943	(15.26, 30.60, 95.87)
16:31391106		P>R	C:947	(1.34, 27.53, 93.97)
16:31391120	rs2230427	F>L	C:952	(-2.94, 14.03, 103.27)
16:31391126		V>M	C:954	(-6.72, 8.24, 105.86)
16:31391151	rs368430021	A>D	C:962	(-14.61, 1.06, 110.25)
16:31391153		V>M	C:963	(-10.59, 1.84, 110.66)
16:31391165		V>M	C:967	(-11.06, 11.68, 109.88)
16:31391172	rs140110829	V>A	C:969	(-7.53, 18.41, 108.64)
16:31391181	rs560912339	P>H	C:972	(-3.11, 24.93, 113.04)
16:31391303		N>H	C:974	(-2.17, 28.79, 109.47)
16:31391309		S>T	C:976	(-9.49, 28.77, 107.05)
16:31391315	rs143932593	R>W	C:978	(-11.59, 26.44, 100.61)
16:31391321		S>P	C:980	(-10.99, 17.60, 99.46)
16:31391324		S>P	C:981	(-13.26, 14.70, 100.29)
16:31391339	rs200363099	P>T	C:986	(-8.76, -0.76, 97.05)
16:31391343	COSM3957509	P>L	C:987	(-7.13, -3.69, 94.57)
16:31391356	rs147269916	F>L	C:991	(-7.92, -9.21, 103.13)
16:31391361	rs181404376	A>V	C:993	(-2.21, -12.91, 102.95)
16:31391366	rs143650639	I>V	C:995	(-1.85, -8.12, 106.41)
16:31391378		P>T	C:999	(1.71, -6.19, 109.85)
16:31391381	rs142434946	V>M	C:1000	(1.25, -3.18, 107.10)
16:31391382		V>A	C:1000	(1.25, -3.18, 107.10)
16:31391612		R>Q	C:1010	(-7.85, 11.59, 97.36)
16:31391617	rs377108919	R>C	C:1012	(-7.60, 18.65, 96.62)
16:31391626		V>I	C:1015	(-1.99, 26.19, 98.92)
16:31391633	rs201868319	S>F	C:1017	(1.25, 31.09, 98.10)
16:31391641	rs370440940	V>I	C:1020	(9.92, 30.61, 100.42)
16:31391662	rs376969995	T>A	C:1027	(-2.83, 17.86, 112.27)
16:31391687	rs371004159	G>V	C:1035	(-13.35, -3.43, 115.57)
16:31391695	rs374327112 COSM557676 COSM3741896	R>C	C:1038	(-12.82, -10.46, 114.88)
16:31391845	rs200993599	I>T	C:1040	(-7.42, -9.32, 110.42)
16:31391874		V>M	C:1050	(0.42, 8.40, 102.89)
16:31391881		E>A	C:1052	(1.75, 12.83, 98.07)
16:31391884		I>S	C:1053	(3.62, 17.77, 98.38)
16:31391887	rs59889488	T>M	C:1054	(1.49, 18.08, 94.89)
16:31391892	rs552106264	D>N	C:1056	(2.16, 22.33, 87.83)
16:31391895		T>A	C:1057	(4.55, 19.09, 86.38)
16:31391901		V>M	C:1059	(6.21, 25.84, 85.60)
16:31392225		T>M	C:1076	(-0.10, 3.83, 114.26)
16:31392234		E>V	C:1079	(-0.06, -4.49, 120.64)
16:31392240		Y>C	C:1081	(-3.53, -10.66, 123.56)

3K72.C | ITGAX.

3K72.C | ITGAX

General Structure Information

Variant Set Distributions

Ripley’s K Analysis Plots

Variant Set Comparisons

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
16:31367953	COSM1717348	V>F	C:32	(32.80, 63.82, 117.68)
16:31368381	COSM1719177	G>S	C:74	(31.42, 59.12, 123.70)
16:31373186	COSM970207	E>K	C:329	(23.03, 40.24, 138.93)
16:31373207	COSM1679045	G>S	C:336	(26.18, 51.63, 126.44)
16:31373216	COSM2917975	A>T	C:339	(24.26, 51.45, 120.57)
16:31373943	COSM471671	E>K	C:391	(23.80, 46.46, 114.31)
16:31373991	COSM2156423	R>C	C:407	(36.58, 36.79, 126.38)
16:31374061	COSM4440406	V>G	C:430	(28.79, 31.57, 114.82)
16:31374313	COSM1609232	T>A	C:454	(19.27, 42.93, 106.15)
16:31374544	COSM1293585	R>H	C:501	(44.91, 47.31, 114.80)
16:31374553	COSM3969547	A>V	C:504	(38.07, 47.79, 114.15)
16:31374634	COSM1377638	R>L	C:531	(51.31, 55.88, 110.26)
16:31382405	COSM1211032	R>W	C:552	(45.36, 50.01, 101.19)
16:31382406	COSM3712027	R>L	C:552	(45.36, 50.01, 101.19)
16:31382998	COSM158644	R>C	C:666	(49.08, 47.38, 60.69)
16:31382999	COSM403529	R>L	C:666	(49.08, 47.38, 60.69)
16:31384596	COSM1518910	N>I	C:779	(20.29, 22.59, 83.70)
16:31390893	COSM970221	E>K	C:913	(8.58, 13.85, 117.38)
16:31390926	COSM1679049	S>P	C:924	(-12.23, -5.88, 126.59)
16:31390930	COSM1679050	E>V	C:925	(-14.58, -4.27, 125.64)
16:31390960	COSM3817885	R>I	C:935	(1.66, 17.51, 114.25)
16:31391310	COSM1724052	S>F	C:976	(-9.49, 28.77, 107.05)
16:31391336	COSM1478839	A>T	C:985	(-11.41, 1.18, 96.19)
16:31391361	COSM1377641	A>V	C:993	(-2.21, -12.91, 102.95)
16:31391381	COSM3711922	V>L	C:1000	(1.25, -3.18, 107.10)
16:31391689	COSM3948503	W>R	C:1036	(-9.58, -2.66, 112.35)
16:31391695	COSM3741896	R>C	C:1038	(-12.82, -10.46, 114.88)