General Structure Information
| PDB ID | 3cjw |
| HGNC Gene Label(s) | NR2F2 |
| Structure Name | crystal structure of the human coup-tfii ligand binding domain |
| Resolution | 1.48Å |
| Reference | AUTH S.W.KRUSE,K.SUINO-POWELL,X.E.ZHOU,J.E.KRETSCHMAN,AUTH 2 R.REYNOLDS,C.VONRHEIN,Y.XU,L.WANG,S.Y.TSAI,AUTH 3 M.J.TSAI,H.E.XUTITL IDENTIFICATION OF COUP-TFII ORPHAN NUCLEARTITL 2 RECEPTOR AS A RETINOIC ACID-ACTIVATED RECEPTOR.REF PLOS BIOL. V. 6 E227 2008REFN ISSN 1544-9173PMID 18798693DOI 10.1371/JOURNAL.PBIO.0060227 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 203 |
| Number Of SNVs | 16 |
| Number Of Permutations | 1812 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.008 |
| p-value | 0.746 |
COSMIC
| Number Of Residues | 203 |
| Number Of SNVs | 4 |
| Number Of Permutations | 197 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.028 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.325 |
| p-value | 0.259 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
