General Structure Information
| PDB ID | 1tev |
| HGNC Gene Label(s) | CMPK1 |
| Structure Name | crystal structure of the human ump/cmp kinase in open conformation |
| Resolution | 2.1Å |
| Reference | AUTH N.SEKULIC,S.ORT,M.KONRAD,A.LAVIETITL SUBSTRATE-INDUCED CONFORMATIONAL CHANGES IN HUMANTITL 2 UMP/CMP KINASE.REF J.BIOL.CHEM. V. 279 33882 2004REFN ISSN 0021-9258PMID 15163660DOI 10.1074/JBC.M401989200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 194 |
| Number Of SNVs | 20 |
| Number Of Permutations | 2254 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.079 |
| p-value | 0.23 |
COSMIC
| Number Of Residues | 194 |
| Number Of SNVs | 3 |
| Number Of Permutations | 139 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.667 |
| p-value | 0.209 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 20 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.54 |
| p-value | 0.164 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
