General Structure Information
| PDB ID | 3nmz |
| HGNC Gene Label(s) | APC |
| Structure Name | crytal structure of apc complexed with asef |
| Resolution | 3.01Å |
| Reference | AUTH Z.ZHANG,L.CHEN,L.GAO,K.LIN,G.WUTITL CRYSTAL STRUCTURE OF APC COMPLEXED WITH ASEFREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 406 |
| Number Of SNVs | 78 |
| Number Of Permutations | 25715 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.049 |
| p-value | 0.415 |
ClinVar
| Number Of Residues | 406 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1901 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.2 |
| p-value | 0.811 |
COSMIC
| Number Of Residues | 406 |
| Number Of SNVs | 7 |
| Number Of Permutations | 5377 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.381 |
| p-value | 0.39 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 78 |
| Number Of ClinVar SNVs | 7 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | -0.036 |
| p-value | 0.795 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 78 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.042 |
| p-value | 0.927 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
