General Structure Information
| PDB ID | 3n8i |
| HGNC Gene Label(s) | ACP1 |
| Structure Name | crystal structure of the a isoform of human cytoplasmic protein tyrosine phosphatase (hcptp-a) in complex with 1-naphtylacetic acid |
| Resolution | 1.5Å |
| Reference | AUTH K.T.HOMAN,D.BALASUBRAMANIAM,C.V.STAUFFACHERTITL STRUCTURAL CHARACTERIZATION OF A SECONDARY BINDING SITE ONTITL 2 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASESREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 154 |
| Number Of SNVs | 42 |
| Number Of Permutations | 3984 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.249 |
| p-value | 0.878 |
COSMIC
| Number Of Residues | 154 |
| Number Of SNVs | 3 |
| Number Of Permutations | 234 |
| Optimal Distance Threshold | 33.0 |
| K Statistic | 0.333 |
| p-value | 0.024 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
