General Structure Information
| PDB ID | 2ksa |
| HGNC Gene Label(s) | TACR1 |
| Structure Name | substance p in dmpc/chaps isotropic q=0.25 bicelles as a ligand for nk1r |
| Resolution | -1.0Å |
| Reference | AUTH A.GAYEN,S.K.GOSWAMI,C.MUKHOPADHYAYTITL NMR EVIDENCE OF GM1-INDUCED CONFORMATIONAL CHANGE OFTITL 2 SUBSTANCE P USING ISOTROPIC BICELLESREF BIOCHIM.BIOPHYS.ACTA 2010REFN ISSN 0006-3002PMID 20937248DOI 10.1016/J.BBAMEM.2010.09.023 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 89 |
| Number Of Permutations | 26937 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.023 |
| p-value | 0.311 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2799 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.4 |
| p-value | 0.43 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 89 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.326 |
| p-value | 0.479 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
