General Structure Information
| PDB ID | 3dzf |
| HGNC Gene Label(s) | CD38 |
| Structure Name | crystal structure of human cd38 extracellular domain complexed with a covalent intermediate, ara-f-ribose-5-phosphate |
| Resolution | 2.01Å |
| Reference | AUTH Q.LIU,I.A.KRIKSUNOV,H.JIANG,R.GRAEFF,H.LIN,H.C.LEE,Q.HAOTITL COVALENT AND NONCOVALENT INTERMEDIATES OF AN NAD UTILIZINGTITL 2 ENZYME, HUMAN CD38.REF CHEM.BIOL. V. 15 1068 2008REFN ISSN 1074-5521PMID 18940667DOI 10.1016/J.CHEMBIOL.2008.08.007 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 252 |
| Number Of SNVs | 66 |
| Number Of Permutations | 36201 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.073 |
| p-value | 0.613 |
COSMIC
| Number Of Residues | 252 |
| Number Of SNVs | 5 |
| Number Of Permutations | 575 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.4 |
| p-value | 0.768 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 66 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.073 |
| p-value | 0.784 |