General Structure Information
| PDB ID | 3ezq |
| HGNC Gene Label(s) | FAS |
| Structure Name | crystal structure of the fas/fadd death domain complex |
| Resolution | 2.73Å |
| Reference | AUTH F.L.SCOTT,B.STEC,C.POP,M.K.DOBACZEWSKA,J.J.LEE,E.MONOSOV,AUTH 2 H.ROBINSON,G.S.SALVESEN,R.SCHWARZENBACHER,S.J.RIEDLTITL THE FAS-FADD DEATH DOMAIN COMPLEX STRUCTURE UNRAVELSTITL 2 SIGNALLING BY RECEPTOR CLUSTERINGREF NATURE V. 457 1019 2009REFN ISSN 0028-0836PMID 19118384DOI 10.1038/NATURE07606 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 113 |
| Number Of SNVs | 22 |
| Number Of Permutations | 5041 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.052 |
| p-value | 0.846 |
ClinVar
| Number Of Residues | 113 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1414 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.857 |
| p-value | 0.081 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 22 |
| Number Of ClinVar SNVs | 7 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.455 |
| p-value | 0.038 |