General Structure Information
| PDB ID | 3dpe |
| HGNC Gene Label(s) | MMP8 |
| Structure Name | crystal structure of the complex between mmp-8 and a non- zinc chelating inhibitor |
| Resolution | 1.6Å |
| Reference | AUTH G.POCHETTI,R.MONTANARI,C.GEGE,C.CHEVRIER,AUTH 2 A.G.TAVERAS,F.MAZZATITL EXTRA BINDING REGION INDUCED BY NON-ZINC CHELATINGTITL 2 INHIBITORS INTO THE S(1) SUBSITE OF MATRIXTITL 3 METALLOPROTEINASE 8 (MMP-8)REF J.MED.CHEM. V. 52 1040 2009REFN ISSN 0022-2623PMID 19173605DOI 10.1021/JM801166J |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 163 |
| Number Of SNVs | 45 |
| Number Of Permutations | 3325 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.094 |
| p-value | 0.439 |
COSMIC
| Number Of Residues | 163 |
| Number Of SNVs | 3 |
| Number Of Permutations | 207 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.667 |
| p-value | 0.464 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
