General Structure Information
| PDB ID | 2qbx |
| HGNC Gene Label(s) | EPHB2 |
| Structure Name | ephb2/snew antagonistic peptide complex |
| Resolution | 2.3Å |
| Reference | AUTH J.E.CHRENCIK,A.BROOUN,M.I.RECHT,G.NICOLA,L.K.DAVIS,AUTH 2 R.ABAGYAN,H.WIDMER,E.B.PASQUALE,P.KUHNTITL THREE-DIMENSIONAL STRUCTURE OF THE EPHB2 RECEPTORTITL 2 IN COMPLEX WITH AN ANTAGONISTIC PEPTIDE REVEALS ATITL 3 NOVEL MODE OF INHIBITION.REF J.BIOL.CHEM. V. 282 36505 2007REFN ISSN 0021-9258PMID 17897949DOI 10.1074/JBC.M706340200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 176 |
| Number Of SNVs | 49 |
| Number Of Permutations | 14954 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.09 |
| p-value | 0.078 |
COSMIC
| Number Of Residues | 176 |
| Number Of SNVs | 4 |
| Number Of Permutations | 15 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.167 |
| p-value | 0.572 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.473 |
| p-value | 0.051 |