General Structure Information
| PDB ID | 3v2w |
| HGNC Gene Label(s) | S1PR1 |
| Structure Name | crystal structure of a lipid g protein-coupled receptor at 3.35a |
| Resolution | 3.35Å |
| Reference | AUTH M.A.HANSON,C.B.ROTH,E.JO,M.T.GRIFFITH,F.L.SCOTT,G.REINHART,AUTH 2 H.DESALE,B.CLEMONS,S.M.CAHALAN,S.C.SCHUERER,M.G.SANNA,AUTH 3 G.W.HAN,P.KUHN,H.ROSEN,R.C.STEVENSTITL CRYSTAL STRUCTURE OF A LIPID G PROTEIN-COUPLED RECEPTOR.REF SCIENCE V. 335 851 2012REFN ISSN 0036-8075PMID 22344443DOI 10.1126/SCIENCE.1215904 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 282 |
| Number Of SNVs | 33 |
| Number Of Permutations | 6923 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.206 |
| p-value | 0.001 |
COSMIC
| Number Of Residues | 282 |
| Number Of SNVs | 11 |
| Number Of Permutations | 10511 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.055 |
| p-value | 0.757 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 10 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.194 |
| p-value | 0.148 |