General Structure Information
| PDB ID | 1h9o |
| HGNC Gene Label(s) | PIK3R1 |
| Structure Name | phosphatidylinositol 3-kinase, p85-alpha subunit: c-terminal sh2 domain complexed with a tyr751 phosphopeptide from the pdgf receptor, crystal structure at 1.79 a |
| Resolution | 1.79Å |
| Reference | AUTH R.A.PAUPTIT,C.A.DENNIS,D.J.DERBYSHIRE,A.L.BREEZE,AUTH 2 S.A.WESTON,S.ROWSELL,G.N.MURSHUDOVTITL NMR TRIAL MODELS: EXPERIENCES WITH THE COLICINTITL 2 IMMUNITY PROTEIN IM7 AND THE P85ALPHA C-TERMINALTITL 3 SH2-PEPTIDE COMPLEXREF ACTA CRYSTALLOGR.,SECT.D V. 57 1397 2001REFN ISSN 0907-4449PMID 11567151DOI 10.1107/S0907444901012434 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 105 |
| Number Of SNVs | 10 |
| Number Of Permutations | 1662 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.044 |
| p-value | 0.127 |
COSMIC
| Number Of Residues | 105 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.967 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
