General Structure Information
| PDB ID | 1rn7 |
| HGNC Gene Label(s) | CST5 |
| Structure Name | structure of human cystatin d |
| Resolution | 2.5Å |
| Reference | AUTH M.ALVAREZ-FERNANDEZ,Y.H.LIANG,M.ABRAHAMSON,X.D.SUTITL CRYSTAL STRUCTURE OF HUMAN CYSTATIN D, A CYSTEINETITL 2 PEPTIDASE INHIBITOR WITH RESTRICTED INHIBITIONTITL 3 PROFILE.REF J.BIOL.CHEM. V. 280 18221 2005REFN ISSN 0021-9258PMID 15728581DOI 10.1074/JBC.M411914200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 112 |
| Number Of SNVs | 45 |
| Number Of Permutations | 5251 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.213 |
| p-value | 0.154 |
COSMIC
| Number Of Residues | 112 |
| Number Of SNVs | 3 |
| Number Of Permutations | 140 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.333 |
| p-value | 0.943 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.333 |
| p-value | 0.617 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
