General Structure Information
| PDB ID | 2yd6 |
| HGNC Gene Label(s) | PTPRD |
| Structure Name | crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase delta |
| Resolution | 1.35Å |
| Reference | AUTH C.H.COLES,Y.SHEN,A.P.TENNEY,C.SIEBOLD,G.C.SUTTON,W.LU,AUTH 2 J.T.GALLAGHER,E.Y.JONES,J.G.FLANAGAN,A.R.ARICESCUTITL PROTEOGLYCAN-SPECIFIC MOLECULAR SWITCH FOR RPTP SIGMATITL 2 CLUSTERING AND NEURONAL EXTENSION.REF SCIENCE V. 332 484 2011REFN ISSN 0036-8075PMID 21454754DOI 10.1126/SCIENCE.1200840 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 194 |
| Number Of SNVs | 52 |
| Number Of Permutations | 17638 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.229 |
| p-value | 0.287 |
COSMIC
| Number Of Residues | 194 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1433 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.19 |
| p-value | 0.003 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 52 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | -0.369 |
| p-value | 0.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
