2KG4.A | GADD45A

PDB ID	2kg4
HGNC Gene Label(s)	GADD45A
Structure Name	three-dimensional structure of human gadd45alpha in solution by nmr
Resolution	-1.0Å
Reference	AUTH R.SANCHEZ,D.PANTOJA-UCEDA,J.PRIETO,T.DIERCKS,M.J.MARCAIDA,AUTH 2 G.MONTOYA,R.CAMPOS-OLIVAS,F.J.BLANCOTITL SOLUTION STRUCTURE OF HUMAN GROWTH ARREST AND DNA DAMAGETITL 2 45ALPHA (GADD45ALPHA) AND ITS INTERACTIONS WITHTITL 3 PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) AND AURORA ATITL 4 KINASEREF J.BIOL.CHEM. V. 285 22196 2010REFN ISSN 0021-9258PMID 20460379DOI 10.1074/JBC.M109.069344

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
1:68151197		S>L	A:7	(-11.06, 19.28, -9.71)
1:68151213		K>N	A:12	(6.30, 16.56, -15.65)
1:68151217		E>K	A:14	(10.97, 12.95, -7.89)
1:68151709		M>L	A:16	(7.89, 14.50, 0.83)
1:68151713		D>G	A:17	(3.73, 14.37, -0.79)
1:68151724		D>Y	A:21	(-0.50, 10.83, -4.47)
1:68151755	rs139216915	L>R	A:31	(-9.95, -3.05, -7.13)
1:68151760		Q>E	A:33	(-6.38, -4.48, -13.36)
1:68151775	rs146431497	V>L	A:38	(-7.00, -7.12, 0.97)
1:68151803	rs150494556	L>P	A:47	(4.58, -17.36, 0.97)
1:68152083		D>G	A:66	(2.19, 1.08, 19.40)
1:68152109		F>L	A:75	(3.42, -4.86, 10.10)
1:68152142		D>Y	A:86	(13.49, -9.74, -4.40)
1:68152170		P>L	A:95	(-3.98, 4.90, 10.43)
1:68152184		E>K	A:100	(-9.53, 7.99, 3.41)
1:68152208		A>P	A:108	(-14.55, -0.64, -4.22)
1:68152235	COSM1296664	E>Q	A:117	(-14.87, -1.00, 18.93)
1:68152239		Q>R	A:118	(-15.04, -4.29, 13.84)
1:68152245		P>Q	A:120	(-6.63, -4.03, 14.72)
1:68152269		T>M	A:128	(0.28, -9.29, -7.38)
1:68153383		Q>E	A:142	(7.90, 8.43, -9.13)
1:68153384		Q>R	A:142	(7.90, 8.43, -9.13)
1:68153401		R>W	A:148	(15.42, -0.11, -4.25)
1:68153408		S>N	A:150	(14.73, 5.44, 1.98)
1:68153410	rs374030083	R>C	A:151	(16.13, -1.37, 1.30)
1:68153411		R>H	A:151	(16.13, -1.37, 1.30)
1:68153414		Y>C	A:152	(21.51, 2.33, -0.68)
1:68153418		M>I	A:153	(19.69, 6.07, 5.65)
1:68153421		D>E	A:154	(20.53, 0.37, 6.91)

2KG4.A | GADD45A.