2J3S.A | FLNA

General Structure Information

PDB ID 2j3s
HGNC Gene Label(s) FLNA
Structure Name crystal structure of the human filamin a ig domains 19 to 21
Resolution 2.5Å
Reference AUTH Y.LAD,T.-R.KIEMA,P.JIANG,O.T.PENTIKANEN,C.H.COLES,AUTH 2 I.D.CAMPBELL,D.A.CALDERWOOD,J.YLANNETITL STRUCTURE OF THREE TANDEM FILAMIN DOMAINS REVEALSTITL 2 AUTO-INHIBITION OF LIGAND-BINDING.REF EMBO J. V. 26 3993 2007REFN ISSN 0261-4189PMID 17690686DOI 10.1038/SJ.EMBOJ.7601827

Variant Set Distributions

ExAC Variants

Number Of Residues 270
Number Of SNVs 42
Number Of Permutations 13989
Optimal Distance Threshold 8.0
K Statistic 0.029
p-value 0.697

Mapped Variants

[+] ExAC Missense Variants