1NN1.A | DTYMK

General Structure Information

PDB ID 1nn1
HGNC Gene Label(s) DTYMK
Structure Name crystal structure of human thymidylate kinase with ddtmp and appnhp
Resolution 1.9Å
Reference AUTH N.OSTERMANN,D.SEGURA-PENA,C.MEIER,T.VEIT,M.MONNERJAHN,AUTH 2 M.KONRAD,A.LAVIETITL STRUCTURES OF HUMAN THYMIDYLATE KINASE IN COMPLEX WITHTITL 2 PRODRUGS: IMPLICATIONS FOR THE STRUCTURE-BASED DESIGN OFTITL 3 NOVEL COMPOUNDSREF BIOCHEMISTRY V. 42 2568 2003REFN ISSN 0006-2960PMID 12614151DOI 10.1021/BI027302T

Variant Set Distributions

ExAC Variants

Number Of Residues 209
Number Of SNVs 60
Number Of Permutations 17344
Optimal Distance Threshold 15.0
K Statistic 0.205
p-value 0.163

Mapped Variants

[+] ExAC Missense Variants